Macrophage subsets in atherosclerosis as defined by single‐cell technologies

Macrophage subsets in human atherosclerosis.

Richness in Architecture as Defined by Contemporary Iranian Television Series

Today, mass media act like a magic mirror, not only reflecting the reality of societies, but also projecting a variety of images onto people’s thoughts. Because of this great ability to produce, reproduce and disperse images, mass media have acquired considerable influence on people’s lives. Among the different media, the television in particular has become an inseparable part of most Iranian h...

Monocyte subsets in atherosclerosis.

Endothelial dysfunction and chronic inflammation of the arterial wall continuously drive the development of atherosclerotic lesions. Monocytes, as cells of the innate immunity, are particularly involved in this process. In the last decade, heterogeneity of circulating monocytes has widely been acknowledged, and a recent consensus nomenclature subdivides classical, intermediate and nonclassical ...

Macrophage Phenotype Modulation by CXCL4 in Atherosclerosis

During atherogenesis, blood monocytes transmigrate into the subendothelial space and differentiate toward macrophages and foam cells. The major driver of monocyte-macrophage differentiation is macrophage colony-stimulating factor (M-CSF). M-CSF-induced macrophages are important promoters of atherogenesis as demonstrated in M-CSF and M-CSF receptor knock out mice. However, M-CSF is not the only ...

B Cell Subsets in Atherosclerosis

Atherosclerosis, the underlying cause of heart attacks and strokes, is a chronic inflammatory disease of the artery wall. Immune cells, including lymphocytes modulate atherosclerotic lesion development through interconnected mechanisms. Elegant studies over the past decades have begun to unravel a role for B cells in atherosclerosis. Recent findings provide evidence that B cell effects on ather...